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gan xing zhuang xi bao diao wang ji zhi yan jiu jin zhan
Author(s): 
Pages: 94-96
Year: Issue:  1
Journal: HEILONGJIANG MEDICINE AND PHARMACY

Keyword:  肝星状细胞细胞凋亡;
Abstract: 肝星状细胞(hepatic stellate cell,HSC) 是肝脏产生细胞外基质的主要来源,其大量增殖和凋亡相对不足在肝纤维化(hepatic fibrosis)的发生中起核心作用,抑制其增殖和诱导其凋亡是逆转肝纤维化的重要对策.肝星状细胞的凋亡受到凋亡和抗凋亡基因、细胞因子等的调控.现将Fas/Fasl系统、Bcl-2、Bax 、p53 、Caspase家族及p53与肝星状细胞凋亡研究概况综述如下.
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