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Efficacy of Chinese Herbal Medicine and Bone Marrow Mesenchymal Stem Cells Transplantation on Heart Function in Rats with Myocardial Infarction:a Meta-analysis
Pages: 673-677
Year: Issue:  6
Journal: Research of Traditional Chinese Medicine

Keyword:  myocardial infarctionbone marrow mesenchymal stem cellsChinese medicinemeta-analysisrat;
Abstract: Objective To systematically evaluate the efficacy of Chinese Medicine and bone marrow mesenchymal stem cells(BMSCs)transplantation in the treatment of myocardial infarction in rats.Methods The animal experiment of Chinese medicine and BMSCs transplantation in the treatment of myocardial infarction were retrieved from China Knowledge Resource Integrated Database(CNKI),Wanfang Data Resource System,VIP network(VIP),PubMed,Embase and other related journals of traditional Chinese medicine.Eight experimental papers were analyzed by meta-analysis using Revman 5.3 software provided by the Cochrane Collaboration.Results The efficacy of left ventricular ejection fraction(LVEF)and shortening fraction(FS)were better in experiment group than that in control group[MD=16.70,95% CI(10.46,22.95),P <0.000 01;MD=15.39,95% CI(11.26,19.52),P <0.000 01].Conclusion Chinese medicine and BMSCs transplantation has obvious effect on heart function in rats with myocardial infarction.
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