Author(s): QIAN Li, GE Kui, XU Bing, WU Jia-jun, WANG Fan-lin, FAN Jing-xian, ZHANG Lin, Department of Emergency, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Department of Radiation Oncology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine
Pages: 167-170
Year: 2018 Issue:  2
Journal: China Journal of Oral and Maxillofacial Surgery
Keyword:  Percutaneous endoscopic gastrostomy; Head and neck cancer; Prophylactic PEG; Reactive PEG;
Abstract: PURPOSE: To investigate the timing of percutaneous endoscopic gastrostomy(PEG) in patients with head and neck cancer undergoing radiotherapy and chemotherapy. METHODS: This retrospective study analyzed the data of patents with head and neck cancer who underwent radio-chemotherapy from January 2016 to December 2016(patients required gastrostomy according to nutritional risk assessed by radiotherapy physicians). With informed consent the patients were divided into chemotherapy before gastrostomy(prophylactic PEG group) and chemotherapy during gastrostomy(reactive PEG group). There were 234 cases in prophylactic PEG group and 93 cases in reaction PEG group. BMI and albumin level of patients were recorded and analyzed before and after cathetering. Wound infections and extubation rates of the two groups were also recorded and compared. SPSS 11.5 software package was used for comparison between the two groups. RESULTS: After chemotherapy and radiotherapy, BMI, albumin and extubation rates of the prophylactic PEG group were significantly higher than those of the reactive PEG group(P<0.01), while the infection rate in the prophylactic PEG group was significantly lower than that in the reactive PEG group(P<0.05). CONCLUSIONS: Prophylactic PEG can improve the nutritional status of patients with head and neck cancer after radiotherapy and chemotherapy, and reduce complications of radiotherapy and chemotherapy.