Clinical research of the lymph node dissection posterior to the right recurrent laryngeal nerve in papillary thyroid carcinoma
Author(s): XU Xiaocheng, DING Jinwang, PENG You, ZHANG Yu, ZHANG Wo, PAN Gang, LUO Dingcun, Department of Thyroid & Breast Surgery, Wujiang First People’s Hospital, Department of Oncology Surgery, Hangzhou First People’s Hospital
Pages: 61-65
Year: 2018 Issue: 2
Journal: Chinese Archives of Otolaryngology-Head and Neck Surgery
Keyword: Thyroid Neoplasms; Risk Factors; Neck Dissection; lymph node posterior to the right recurrent laryngeal nerve;
Abstract: OBJECTIVE To invest igate the clinical value of the lymph nodes posterior to the right recurrent laryngeal nerve(LN-prRLN, right VI-2) dissection in papillary thyroid carcinoma(PTC). METHODS We studied the relationships between LN-prRLN metastasis and the clinicopathological characteristics in 408 patients with right or bilateral PTC who underwent LN-prRLN dissection. RESULTS Right VI-2 lymph node metastasis was 16.67%. Single factor analysis showed that there were statistically significant correlations between right VI-2 metastasis and gender,age,size and number of right thyroid lobe tumor, capsular invasion, right VI-1 lymph node metastasis and their size,and also metastatic lymph node in the right cervical lateral compartment. Multivariate Logistic regression analysis showed that Right VI-2 lymph node metastasis was related to right tumor size, capsular invasion, the right VI-1 metastasis and right lateral lymph node metastasis(P <0.05). The receiver-operator characteristic(ROC) analysis showed that the risk factors of LN-prRLN: age <35.5 years, right tumor size >0.85 cm,lymph node(right VI-1) number >1.5, metastatic lymph node(right VI-1) size >0.45 cm, lymph node number in the right cervical lateral compartment >0.5 and the areas under the ROC curves were 0.585, 0.787, 0.788, 0.725, 0.719.CONCLUSION The dissection of LN-prRLN should be considered when patient with the risk factors such as male, age <35.5 years, right tumor size >0.85 cm, capsular invasion, lymph node(right VI-1) number >1.5, metastatic lymph node(right VI-1) size >0.45 cm, lymph node number in the right cervical lateral compartment >0.5.
Pages: 61-65
Year: 2018 Issue: 2
Journal: Chinese Archives of Otolaryngology-Head and Neck Surgery
Keyword: Thyroid Neoplasms; Risk Factors; Neck Dissection; lymph node posterior to the right recurrent laryngeal nerve;
Abstract: OBJECTIVE To invest igate the clinical value of the lymph nodes posterior to the right recurrent laryngeal nerve(LN-prRLN, right VI-2) dissection in papillary thyroid carcinoma(PTC). METHODS We studied the relationships between LN-prRLN metastasis and the clinicopathological characteristics in 408 patients with right or bilateral PTC who underwent LN-prRLN dissection. RESULTS Right VI-2 lymph node metastasis was 16.67%. Single factor analysis showed that there were statistically significant correlations between right VI-2 metastasis and gender,age,size and number of right thyroid lobe tumor, capsular invasion, right VI-1 lymph node metastasis and their size,and also metastatic lymph node in the right cervical lateral compartment. Multivariate Logistic regression analysis showed that Right VI-2 lymph node metastasis was related to right tumor size, capsular invasion, the right VI-1 metastasis and right lateral lymph node metastasis(P <0.05). The receiver-operator characteristic(ROC) analysis showed that the risk factors of LN-prRLN: age <35.5 years, right tumor size >0.85 cm,lymph node(right VI-1) number >1.5, metastatic lymph node(right VI-1) size >0.45 cm, lymph node number in the right cervical lateral compartment >0.5 and the areas under the ROC curves were 0.585, 0.787, 0.788, 0.725, 0.719.CONCLUSION The dissection of LN-prRLN should be considered when patient with the risk factors such as male, age <35.5 years, right tumor size >0.85 cm, capsular invasion, lymph node(right VI-1) number >1.5, metastatic lymph node(right VI-1) size >0.45 cm, lymph node number in the right cervical lateral compartment >0.5.
Related Articles