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Advances in tracheal transplantation
Author(s): Cui Pengcheng
Pages: 73-
75
Year: 2018
Issue:
1
Journal: Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Keyword: Trachea; Transplantation; homologous; Neovascularization; physiologic; Immunosuppression;
Abstract: The length of tracheal defect or stenosis exceeded 5 cm could not be treated by simple resection and end-to-end anastomosis of the remaining trachea.Various ways of tracheal replacement had appeared sequentially,such as radial forearm free flap with cartilage grafts,tracheal tissue-engineering and tracheal allotransplantation.Among these methods,tracheal allotransplantation displayed a better long-term result.In this review,we are focused on recent advances in tracheal allotransplantation,particularly on revascularization and reepithelialization of graft,as well as on the application of immunosuppressive agents.
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