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Expression of BAP1 in the oral cancer tissue
Author(s): 
Pages: 68-70
Year: Issue:  18
Journal: General Journal of Stomatology

Keyword:  BAP1 proteinOral carcinomaImmunohistochemistrySemi-quantiative analysis;
Abstract: Objective This study aims to evaluate expression of BAP1 protein in the oral carcinoma tissue and normal oral tissue to see if there is difference and discuss the potential mechanism behind it.Methods Expression of BAP1 protein in 20 cases of oral carcinoma tissues,20 cases of normal oral tissues were detected by immunohistochemistry.Semi-quantiative analysis was deployed to calculate the expression.Results BAP1 protein expression was low in oral carcinoma tissues while relatively high in normal oral tissues,the difference was statistically significant(P<0.05).Conclusion The expression of BAP1 protein declined remarkably in the oral carcinoma tissue and BAP1 plays a vital role in the genesis of oral cancer.
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