The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
Recurrence of epidemic parotitis after vaccination of parotitis vaccine
Author(s): 
Pages: 403-405
Year: Issue:  8
Journal: MODERN PRACTICAL MEDICINE

Keyword:  流行性腮腺炎/预防和控制腮腺炎病毒腮腺炎疫苗碱基序列;
Abstract: 目的探讨接种腮腺炎疫苗后再感染流行性腮腺炎的原因. 方法对115例接种腮腺炎疫苗后再发生流行性腮腺炎的患儿血清,用单链构象多态性分析(PCR-SSCP)法分离得到流行株与疫苗株的核苷酸序列,分析其分子生物学特点. 结果流行株与疫苗株的核苷酸序列相差8个核苷酸,流行株之间有1~2个核苷酸差异. 结论接种腮腺炎疫苗后再发生感染的原因可能是流行株与疫苗株核苷酸序列相差太大,从而导致疫苗保护力不足,引起再次发病.
Related Articles
No related articles found