The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
An open label multi-center clinical trial to evaluate the efficacy of compound phenylpropanolamine hydrochloride sustained release capsules in patients with nasal symptoms associated with common cold
Author(s): 
Pages: 547-549
Year: Issue:  8
Journal: CHINESE JOURNAL OF INTERNAL MEDICINE

Keyword:  感冒鼻部症状麻黄碱临床研究;
Abstract: 目的观察复方盐酸伪麻黄碱缓释胶囊治疗普通感冒和(或) 流行性感冒患者鼻部症状的临床疗效和安全性.方法采用开放、多中心临床研究.共纳入受试者419例.合格的受试者每次1粒、每日2次、间隔12 h、连服4 d复方盐酸伪麻黄碱缓释胶囊,然后观察患者鼻部症状的改善情况.结果本研究最终有416例患者可供疗效分析和安全性分析.鼻塞症状1至4 d每日治愈率分别为7%、31%、64%和88%,流涕症状1至4 d每日治愈率分别为9%、36%、68%和89%,打喷嚏症状1至4 d每日治愈率分别为20%、51%、76%和93%,流眼泪症状1至4 d每日治愈率分别为36%、68%、89%和96%.共有35例患者发生了40次不良反应,发生率为8.4%(35/416),主要为轻、中度嗜睡及口干,未出现严重的不良反应.结论复方盐酸伪麻黄碱缓释胶囊可明显持续控制普通感冒和(或)流行性感冒的鼻部症状,疗效较高,耐受性较好.
Related Articles
No related articles found