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The curative effect of anastrozole combined with radiotherapy in treating the early breast cancer in elderly patients
Pages: 509-511
Year: Issue:  5
Journal: Oncology Progress

Abstract: Objective To evaluate the clinical curative effect and quality of life of anastrozole combined with radio-therapy treatment in elderly patients with early breast cancer. Method 98 cases of elderly females who underwent breast-conserving surgery were retrospectively analyzed, the study group (n=45) was given anastrozole combined with auxiliary radiation, while the control group (n=53) was given conventional endocrine therapy of anastrozole, and the 5-year cumula-tive survival rate, recurrence rate, and quality of life of all patients were observed. Result The 5-year cumulative surviv-al rates were 80.0%and 64.2%in study group and control group, respectively, with statistically significant difference ob-served (P<0.05);the recurrence rate in study group was 24.4%(11/45), significantly lower than that in the control group at 45.3%(24/53) (P<0.05);besides, after treatment for 3 months, patients in study group had worse quality of life com-pared with control group (P<0.01), but in 6 months and 12 months after therapy, the quality of life in both groups were similar (P>0.05). Conclusion Anastrozole combined with radiotherapy increases the survival rate while reduces the re-currence rate in elderly patients with early breast cancer after surgery.
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