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A comparison study of short-term outcomes and the serological changes between laparoscopic-assisted D2 radical total gastrectomy and traditional open gastrectomy for gastric cancer
Pages: 528-530,550
Year: Issue:  5
Journal: Oncology Progress

Abstract: Objective To compare the short-term outcomes and the serological changes in gastric cancer patients re-ceiving laparoscopic-assisted D2 radical total gastrectomy and traditional open gastrectomy. Method A total of 118 cas-es who were diagnosed as gastric cancer were included in the study, laparoscopic-assisted D2 radical total gastrectomy (laparoscopic surgery group, n=59) or traditional open gastrectomy (open surgery group, n=59) were administered as per patients'intention and respective surgery strategy, the intra-operative and post-operative measures, as well as serological changes in both groups were compared. Result The operative time was shorter, intra-operative blood loss was less, and incision length was trimmed in laparoscopic surgery group compared with open surgery group (P<0.05);both groups had similar number of resected lymph nodes (P>0.05); patients receiving laparoscopic surgery were observed with shorter time to first flatus, time to eat liquid and semi-liquid food, and decreased hospital stay compared with those underwent open surgery (P<0.05);in 72 h after surgery, there was no significant differences between the two groups in regard of liv-er and kidney function indexes of ALT, AST, ALB, BUN and inflammation related indexes such as WBC, NE, and CRP (P>0.05), but the Cr level of laparoscopic surgery group was higher than that of the open surgery group, the difference was statistically significant (P<0.05). Conclusion Laparoscopic-assisted D2 radical total gastrectomy is a safe and effec-tive procedure in treating gastric cancer, with minimal invasiveness and enhanced post-operative recovery, and is worth clinical application.
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