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Subtype characteristics of human papilloma virus infection in young women and middle-aged women
Pages: 587-588
Year: Issue:  5
Journal: Oncology Progress

Abstract: Objective To investigate the subtype characteristics of human papilloma virus (HPV) infection in young women and middle-aged women. Method Cervical epithelial cell samples of 387 female patients were collected during gynecological examination, and RCP-reverse dot bolt assay was used to detect 11 genotypes in the samples;the patients were divided into young group (25 to 35 years old) and middle-aged group (36 to 55 years old) according to age distribu-tion, and the infection and subtype distribution of the two groups were compared. Result 21 of the 387 female patients were infected with HPV, and the total infection rate was 5.4%. There were 96 patients in young group, 9 of them were in-fected, and the infection rate was 9.4%;there were 291 patients in middle-aged group, 12 of them were infected, and the infection rate was 4.1%. The high-risk HPV subtypes with relatively high infection rate in two groups were HPV16 and HPV58. In young group, 8 patients had infections of single HPV subtype, and one patient was infected with multiple HPV subtypes (1.0%). In middle-aged group, 9 patients had infections of single HPV subtype, and 3 patients were infect-ed with multiple HPV subtypes (1.0%). The infection rates of multiple HPV subtypes were similar between two groups. Conclusion The incidence of HPV infection and the distribution of virus subtypes vary in different age groups, single type infection and high risk infection are dominant infection types, and the most common high-risk type is HPV16, fol-lowed by HPV58.
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