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Relationship Between TRIM44 Expression and Prognosis of Gastric Cancer
Pages: 195-197
Year: Issue:  3
Journal: Journal of Basic and Clinical Oncology

Abstract: 目的 探讨TRIM44蛋白在胃癌组织中的表达情况以及其对胃癌发生、发展的影响.方法 入组60例确诊并接受根治术的胃癌患者,用免疫组化方法检测60例胃癌组织中TRIM44蛋白的表达情况.结果 TRIM44蛋白在胃癌组织中高表达,表达率为28.3%(17/60),且其表达与2~3个区域淋巴结侵犯、高复发率密切有关(P<0.05);TRIM44蛋白高表达组的预后较低表达组差(P<0.05).结论 TRIM44蛋白在胃癌组织中高表达与肿瘤的淋巴侵犯以及高复发率有关,且TRIM44蛋白高表达的胃癌患者总生存更差.
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