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Value of Cyclooxidase-2 and Vascular Endothelial Growth Factor in the Diagnosis and Classification of Meningioma
Pages: 220-221
Year: Issue:  3
Journal: Journal of Basic and Clinical Oncology

Abstract: 目的 探讨环氧化酶-2(COX-2)、血管内皮生长因子(VEGF)在脑膜瘤诊断及分级中的应用价值.方法 采用免疫组化S-P法检测76例脑膜瘤组织中COX-2、VEGF的表达,并分析两者在脑膜瘤诊断中的价值以及对分级的影响.结果 76例脑膜瘤组织中COX-2、VEGF的阳性率分别为69.73%(53/76)、63.16%(48/76).随着脑膜瘤级别的升高,COX-2、VEGF的阳性率逐渐升高.结论 脑膜瘤高表达COX-2、VEGF,且阳性率随着脑膜瘤级别的升高而升高,这提示COX-2、VEGF可用于脑膜瘤的诊断及级别评定.
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