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Analysis of 47 Cases of Adverse Drug Reactions Induced by Imatinib
Pages: 222-224
Year: Issue:  3
Journal: Journal of Basic and Clinical Oncology

Abstract: 目的 探讨伊马替尼所致不良反应(ADR)的特点,为临床合理用药提供数据参考.方法 对我院2015年至2016年上报的47例伊马替尼ADR报告按患者年龄、性别、给药途径、药品种类、ADR临床表现等进行统计分析.结果 47例ADR中,≤20岁和51~60岁患者发生ADR最多(78.72%);80.85%的ADR在用药15 d内发生;血液学ADR占68.09%、皮肤及其附件ADR占70.21%、消化系统ADR占87.23%.结论 伊马替尼ADR多数表现轻微,采取适当的处理可提高患者用药依从性,且用药过程中需加强对患者的随访观察,防止严重ADR的发生.
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