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Quantitative analysis of the carotid artery atherosclerotic plaque volume by using real-time three-dimensional ultrasonography
Pages: 533-537
Year: Issue:  5
Journal: Radiologic Practice

Abstract: Objective:To investigate the feasibility and accuracy of carotid plaque volume quantitative analysis by using real-time three-dimensional ultrasonography (RT-3DU).Methods:Twenty-three patients with carotid atherosclerosis were examined by the RT-3DU.The volume measurements were obtained by two sonographers according to the randomized double-blind protocol The same volume quantification procedure was repeated by one of the two observers one month later.Results:The volume of the 35 plaques quantitatively measurd by RT-3DU was (171 ± 116)mm3.For the plaque volume,the Bland-Altman plots showed that only 2.9 % (1/35) of the scatter points were outside the 95 % limits of the agreement,and there was only 1.51mm3 volume difference between the absolute value of the mean difference and the baseline with a mean difference of 0;For lumen volume stenosis,the Bland-Altman plots showed that only 2.9% (1/35) of the scatter points were outside the 95% limits of the agreement,there was only 0.63% difference between the absolute value of the mean difference and the baseline with a mean difference of 0.The intraclass correlation coefficient was greater than 0.900,which indicated no statistical significant difference within intra-observer and inter-observer measurements.Conclusion:The spatial form of the entire plaque can be displayed by RT-3DU.The quantitative determinations of plaque volume and lumen volume stenosis display a high level of reproducibility.
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