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Application of MR mDIXON-quant technique in accurate quantification of liver fat content in type 2 diabetic patients with non-alcoholic fatty liver disease
Pages: 451-455
Year: Issue:  5
Journal: Radiologic Practice

Abstract: Objective:To investigate the application value of MR mDIXON-quant technique in accurate quantification of liver fat content in type 2 diabetic patients with non-alcoholic fatty liver disease (NAFLD).Methods:98 subjects were studied in this research,including 33 males and 16 females in diabetic group,33 males and 16 females in control group (non-diabetic group).All subjects underwent liver MR mDIXON-quant imaging,and liver fat content was measured on MR workstation.The difference of detection rate of non-alcoholic fatty liver was compared between the two groups.Results:The median fat content of liver was 5.5% (first quartile 3.8%,third quartile 11.0%) in diabetic group and 3.7% (first quartile 2.5%,third quartile 5.7%) in control group.The total detection rate of fatty liver was 59.2% in diabetic group,and 30.3% in control group.In the male subjects,the detection rate of fatty liver in diabetic group (63.6%,21/33) was higher than that in control group (30.3 %,10/33),and the difference was statistically significant.In female subjects,the detection rate of fatty liver in diabetic group (50%,8/16) was higher than that in control group (25%,4/16),and the difference was not statistically significant.Conclusion:Quantification of liver fat content by MR mDIXON-quant technique was convenient and accurate,and it may provide important reference for assessment of screening,diagnosis and therapeutic effect of type 2 diabetic patients with NAFLD.
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