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e xing wai zhou shen jing qiao liu 52 li lin chuang bing li fen xi
Pages: 91-92
Year: Issue:  12
Journal: Chinese Journal of Practical Nervous Diseases

Abstract: 目的 探讨恶性外周神经鞘瘤(MPNST)的临床病理情况.方法 纳入我院2011-06-2014-06收治的恶性外周神经鞘瘤患者52例为研究对象,收集所有患者临床病理学和免疫学资料,观察恶性外周神经鞘瘤的临床病理特点.结果 头颈部和四肢的发生率分别为30.77%、25.00%,明显高于其他部位.所有患者肿瘤细胞S-100蛋白局部病灶阳性,阳性率高达100%.其余表型多呈阴性,阳性率较低.随访2 a复发率58.33%,复发患者均在1~12个月内死亡;无瘤生存率33.33%.结论 恶性外周神经鞘瘤组织形态复杂,尤其需要与各种肿瘤类型进行鉴别诊断,病死率和复发率极高,预后情况差.
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