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dan tuo ye suan shen jing jie zuo zhi zhi liao hie de liao xiao ji dui tnf- he il-6 de ying xiang
Pages: 107-108
Year: Issue:  12
Journal: Chinese Journal of Practical Nervous Diseases

Abstract: 目的 探讨单唾液酸神经节苷脂注射液治疗新生儿缺氧缺血性脑病的效果及对TNF-α和IL-6的影响.方法 回顾分析我院2014-03-2015-09收治的104例新生儿缺氧缺血性脑病患儿,随机分为2组,研究组52例采用单唾液酸神经节苷脂注射液治疗,对照组52例采用常规对症治疗,比较2组治疗效果及TNF-α、IL-6指标的变化.结果 研究组有效率(96.15%)与对照组(82.69%)比较差异有统计学意义(P<0.05);治疗后研究组CT值、NBNA评分改善程度与对照组比较差异有统计学意义(P<0.05);研究组TNF-α、IL-6均低于对照组,差异有统计学意义(P<0.05);2组均未发生严重不良反应.结论 单唾液酸神经节苷脂注射液治疗新生儿缺氧缺血性脑病效果显著,可明显改善患儿脑神经功能,安全性好,值得临床推广应用.
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