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Correlation of Brain Natriuretic Peptide in Blood Plasma and Prognosis of Acute Ischemic Stroke Patients
Pages: 204-205,224
Year: Issue:  3
Journal: Neural Injury and Functional Reconstruction

Abstract: Objective:To explore the correlation of brain natriuretic peptide (BNP) in blood plasma and prognosis of acute ischemic stroke patients.Methods:Two hundred and twelve patients of acute ischemic stroke were divided into survival group and death group according to whether death or not during they were in hospital.The clinical data of 2 groups were compared,and diagnostic effect with BNP and NIHSS score screening prognosis of acute ischemic stroke were analyzed.Results:The death rate of prognosis of acute ischemic stroke in the duration of hospital stay was 15.09% (32/212).Multiple risk factors analysis showed that atrial fibrillation (OR=3.819),cerebral infarction of a large area (OR=6.228),BNP of blood plasma ≥280 ng/L (OR=5.191) and NIHSS score ≥ 13 (OR=3.536) were the independent risk factors of prognosis death of acute ischemic stroke.The sensitivity,specificity and accuracy of NIHSS score≥ 13 screening prognosis were respectively 89.1%,75.0% and 87.0%,and BNP≥280 ng/L respectively 85.0%,81.3% and 84.4%.Conclusion:Atrial fibrillation,cerebral infarction of a large area,BNP of blood plasma and NIHSS score are the high risk factors of prognosis death of acute ischemic stroke.Of the total,BNP of blood plasma and NIHSS score may be predictive indexes of prognosis death of acute ischemic stroke.
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