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Low Serum Level of Cystatin C is Closely Associated with Cerebral Aneurysm
Pages: 206-208
Year: Issue:  3
Journal: Neural Injury and Functional Reconstruction

Abstract: Objective:To investigate the connection within serum cystatin C levels and subarachnoid hemorrhage (SAH) or intracranial aneurysm.Methods:Fifty two patients with non-aneurysm subarachnoid hemorrhage (SAH group),81 inpatient with intracranial aneurysm and without subarachnoid hemorrhage (aneurysm group),75 inpatient with aneurysmal subarachnoid hemorrhage (aSAH group),and 124 inpatient with benign paroxysmal positional vertigo (BPPV) as control group were randomly enrolled.A retrospective survey on the serum level of cystatin C and other related serological index were conducted.Results:The serum level of cystatin C in aneurysmal subarachnoid hemorrhage group and intracranial aneurysm group was significantly lower than thosein control group and non-aneurysm subarachnoid hemorrhage group (P<0.05).There was positive correlation between the serum level of cystatin C and the serum level of uric acid.Conclusion:The patients with intracranial aneurysm has lower serum level of cystatin C,and the cystatin C may be associated with cerebral aneurysm,but it has no relationship with subarachnoid hemorrhage.
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