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China/Asia On Demand
Journal Articles
Construction and information analysis of bacteriocins database
Pages: 418-424
Year: Issue:  5
Journal: Chinese Journal of Antibiotics

Abstract: Objective To establish a database of bacteriocins,and analyze the known information of bacteriocins,which could help the design and development of novel bacteriocins.Methods We retrieved the large protein database and collected bacteriocins reported in the literature.The database was built on Linux platform with tools including MySQL,Perl,phpMyAdmin,Apache,FileZilla,HTML,and PHP.Results The database harbors 407 bacteriocins,43 PDB structures and 2105 pieces of activity data.Annotations of one bacteriocin in the database contain the sequence,the modification,the source,the classification,the structure,the activity,the reference and physicochemical parameters.A user-friendly website(AMPs from Bacterial database, was established to provide searching,browsing and blast functions.Conclusion In this study,the database of bacteriocins containing comprehensive information was established,which can promote the development of novel bacteriocins.
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