The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
Usefulness of Proton MR Spectroscopy for the Differential Diagnosis Between Encephalitis and Glioma Mimicking Encephalitis
Author(s): 
Pages: 1796-1800
Year: Issue:  12
Journal: Journal of Clinical Radiology

Keyword:  Proton MR spectroscopyEncephalitisGlioma mimicking encephalitisDifferential diagnosis;
Abstract: 目的 利用多体素氢质子磁共振波谱(1 H-MRS)分析脑炎与脑炎样胶质瘤的差别,探讨1H-MRS的鉴别诊断价值.方法 搜集经手术或活检病理证实的脑炎样胶质瘤患者11例,经手术或病理活检证实、或多次随访确诊的脑炎患者14例.两组患者均行MRI平扫和增强扫描及多体素1 H-MRS(PRESS序列,TR/TE=2000 ms/135ms).选择位于病灶强化区或T2WI高信号区的体素,分析N-乙酰天门冬氨酸(NAA)、胆碱(Cho)、肌酸(Cr)、肌醇(MI)峰下面积值及比值,并以对侧正常脑实质的波谱为参照作进一步分析.结果 与脑炎相比,胶质瘤的1H-MRS具有以下特点:(1)NAA峰下面积显著降低(P=0.004)而MI峰下面积显著增高(P =0.002),Cho与Cr峰下面积无显著差异(P>0.05);(2)峰下面积比值NAA/Cr(P=0.033)与NAA/Cho(P=0.001)显著降低,而MI/Cr(P=0.003)与Cho/NAA(P=0.022)显著升高,Cho/Cr无显著差异(P =0.097);(3)病灶区代谢物与健侧肌酸峰下面积(Cr-n)比值中,胶质瘤NAA/Cr-n显著降低(P=0.018)而MI/Cr-n(P<0.001)和Cho/Cr-n(P=0.003)显著升高.结论 1H-MRS作为一种无创伤性检查手段,可为脑炎与脑炎样胶质瘤的鉴别诊断提供重要依据.
Related Articles
No related articles found