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Research of polymyxin heteroresistance in Acinetobacter baumannii
Author(s): Qian Liu-jia, Chen Dai-jie, Lin Hui-min
Pages: 207-
211
Year: 2017
Issue:
3
Journal: Chinese Journal of Antibiotics
Keyword: Heteroresistance; Adaptive resistanc; Acinetobacter baumannii; Polymyxins;
Abstract: "Heteroresistance" describes a phenomenon where subpopulations of seemingly isogenic bacteria exhibit a range of susceptibilities to a particular antibiotic.Heteroresistance in Acinetobacter baumannii displays where subpopulations grew from 3 to 10μg/mL colistin while the culture's MIC ranged from 0.25 to 2μg/mL.This article reviews the definition,detection methods,clinical significance and control strategies by comparing heteroresistance.
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