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The serological epidemiological investigation of Chuzan disease by micro-neutralization test in China
Author(s): 
Pages: 1-4
Year: Issue:  1
Journal: Chinese Journal of Preventive Veterinary Medicine

Keyword:  Chuzan diseasemicro-neutralization testserological epidemiological investigation;
Abstract: A Chuzan virus (CHUV) was initially isolated by our laboratory from the sentinel cattle in Guangxi province of China in 2014. To investigate the epidemic distribution of Chuzan disease in China, a total of 543 bovine and goat sera derived from 9 provinces were detected for the neutralizing antibodies against CHUV by micro-neutralization test. The highest positive rate of CHUV was up to 57.35% (39/68) in Hainan province, and the samples from Heilongjiang province were all negative. The positive rates in other provinces were between 6% and 48.65 %. The results indicated that Chuzan disease was epidemic severely in 8 of 9 provinces, and the infection rate in the south part of China was higher. The positive rate of bovine sera (6%-58.5%) was higher than goat sera (16.67%-33.33%) in seven provinces except of Xinjiang province. In addition, the results showed that the infection rate in autumn (September to November) was the highest (16.67%-43.33%), which was significantly higher than that in spring and summer. Due to the representative of collected sera from 9 provinces, these data of serological epidemiological investigation shows that Chuzan disease prevalence in China is extensive.
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