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Suanzaoren Decoction(酸枣仁汤) combined with Flupentixol and Melitracen Tablets and Oryzanol in the Treatment of Perimenopausal Depression Randomized Controlled Study
Pages: 55-57
Year: Issue:  9
Journal: Journal of Practical Traditional Chinese Internal Medicine

Keyword:  peri menopausal depressiondroperidol flupentixol and melitracenoryzanolSuanzaoren decoction(酸枣仁汤)therapy of combining traditional Chinese and western medicinerandomized controlled study;
Abstract: [Objective] To observe the Suanzaoren Decoction Combined with Flupentixol and melitracen tablets and oryzanol in the treatment of perimenopausal depression effect. [Methods] 60 outpatients were randomly divided into two groups according to the method of random parallel control. The control group of 30 cases of Flupentixol and melitracen tablets, 0.5 mg/times, 2 times/d, oral; oryzanol, 10 mg/times, 3 times/d, oral. Treatment group, 30 cases of Suanzaoren Decoction(Suanzaoren 30 g, Szechuan lovage rhizome, Poria, Anemarrhena 12 g, licorice 6 g; liver depression of the fire add gardenia, cortex moutan; phlegm heat disturbance and Rhizoma Coptidis, Trichosanthes, gardenia; Yin deficiency and fire wangka dry lotus seed, Ligustrum lucidum, Lily and Rehmannia glutinosa; due to deficiency of Qi and blood, blood Yangxin sunburn and licorice), daily 1 agent, water to cook 400 ml, 2 times daily; western medicine in the treatment of with the control group. Continuous treatment for 1 courses of 15 d. Observation of clinical symptoms, HAMD score, adverse reaction. Treatment of 1 courses of treatment(15 d), determine the efficacy. [Results] The treatment group, 8 cases recovered, 10 cases were markedly effective, 11 cases were effective, 1 case ineffective, effective rate is 96.67%; control group, 4 cases were cured, 8 cases were markedly effective, 9 cases were effective, 9 cases ineffective, efficient 70.00%. The treatment group curative effect surpasses the control group(P<0.05). HAMD score of two groups were improved(P<0.01), the treatment group improved better than the control group(P<0.01). [Conclusion] Suanzaoren Decoction Combined with droperidol thiadiazole tons and deanxit and oryzanol treatment of perimenopausal depressive disorder, and the results were satisfactory. No serious adverse reactions, worthy of promotion.
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