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The Apoptosis in Damaged Testicular Tissue Caused by Varicocele
Author(s): 
Pages: 414-415
Year: Issue:  6
Journal: NATIONAL JOURNAL OF ANDROLOGY

Keyword:  动物模型精索静脉曲张凋亡低生育力大鼠;
Abstract: 目的:探讨外科所致的精索静脉曲张对大鼠生精细胞凋亡的影响.方法:采用成年雄性Wistar大鼠复制左精索静脉曲张模型;用原位末端脱氧核苷酸转移酶标记法(TUNEL)检测睾丸生精细胞凋亡.结果:实验组的细胞凋亡率显著高于假手术对照组(P<0.05).结论:外科所致的精索静脉曲张大鼠睾丸生长减缓,生精细胞凋亡增加,这可能是其影响生育能力的机制之一.
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