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Study on Hypolipidemic Effect of Compound Bulbus Allii Polyrhizi Granules
Pages: 57-59
Year: Issue:  7
Journal: Journal of Liaoning College of Traditional Chinese Medicine

Keyword:  Compound Bulbus Allii Polyrhizi Granuleshypolipidemichypoglycemicliver indexTGTCHDL-CLDL-C;
Abstract: Objective:Study on hypolipidemic effect of the compound Bulbus Allii Polyrhizi Granules on experimental rats,providing basis for the development of drugs and health food. Methods:50 Wistar rats in health,were divided randomly into 5 groups,ten one group:three drug groups,high concentration group(800 mg·kg-1·d-1),medium concentration group(400 mg·kg-1·d-1),low concentration group(200 mg·kg-1·d-1)were designed giving Compound Bulbus Allii Polyrhizi Granules of different concentration by gavage once a day.And another two groups:normal control group,model group were set as comparison.Test and inspect the exchange of body weight,liver index,glucose(Glu),triglycerides(TG),total cholesterol(TC),high-density lipoprotein(HDL-C),and low density lipoprotein(LDL-C)in the rats. Results:The lever of Glu,TC,TG,LDL-C of the model group was dramatically higher than the blank group,while the HDL-C was lower,thus the modle was successfully set. The weight of the rats,liver index,Glu,TC,TG,LDL-C of drug groups were appearancelly lower than model group,while HDL-C was higher. Conclusion:Compound Bulbus Allii Polyrhizi Granules can significantly reduce the weight of rats,lever of Glu,TC,TG,LDL-C,liver index of experimental hyperlipidemia rats,and increase lever of HDL-C of experimental hyperlipidemia rats,thus had significant hypolipidemic and hypoglycemic effects.
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