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Influence of Hypoglycemic Effect and Inflammatory State for Treating Spleen and Stomach Stagnation Syndrome Diabetes Patients with Houpo Sanwu Decoction
Pages: 164-166
Year: Issue:  7
Journal: Journal of Liaoning College of Traditional Chinese Medicine

Keyword:  type 2 diabetes metillusspleen and stomach stagnation syndromeHoupo Sanwu Decoctionhypoglycemic effectinflammatory factor;
Abstract: Objective:To investigate the clinical efficacy of treating spleen and stomach stagnation syndrome diabetes patients with Houpo Sanwu Decoction,and explore the influence of hypoglycemic effect and inflammatory state. Methods:120 2 diabetes patients were randomly divided into a control group of 60 cases and an observation group of 60 cases. Patients in the control group were treated with metformin hydrochloride tablets;while patients in the observation group were treated with Houpo Sanwu Decoction,15 days for a course,4 courses for treatment. The research was aimed at observing the improvement of the main clinical symptoms,evaluating its syndrome integral,monitoring the changes of glucose and insulin levels,observing the efficacy of the drug,and testing the inflammatory factor levels. Results:The improvement of main clinical symptoms for the patients in the observation group was better than that for the patients in the control group,the symptoms score was shorter than that of the control group,and the efficiency was 91.7%,which was higher than that of the control group 76.7%(P<0.05);observation group of patients with hypoglycemic effect was better than that of the control group patients,and the insulin resistance was also improved more significantly than that of the control group patients,the levels of FPG,2 h PG,Hb A1 C,FINS and HOMA-IR were lower than that of the control group patients(P<0.05);the levels of hs-CRP,IL-6 and TNF-αwere lower than that of the control group patients(P<0.05). Conclusion:Houpo SanwuDecoction has good hypoglycemic effect,it can improve the patients’ clinical symptoms,the mechanism may be associated with reducing the levels of inflammatory factors,is worth of wide application in the clinical practice.
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