Analysis on distribution and drug resistance of pathogenic bacteria in the First People’s Hospital of Xuzhou from 2013 to 2015
Author(s): ZHU Jie-pin, JIANG Fan-jing, Department of Pharmacy, The First People’s Hospital of Xuzhou
Pages: 2052-2056
Year: 2016 Issue: 12
Journal: World Phytomedicines
Keyword: pathogenic bacteria; drug resistance; hospital infection;
Abstract: Objective To investigate the distribution and drug resistance of pathogenic bacteria in the First People’s Hospital of Xuzhou from 2013 to 2015. Methods A retrospective analysis from January 2013 to December 2015 in the First People’s Hospital of Xuzhou were collected on the clinical data of patients with nosocomial infection, and the distribution and drug resistance of pathogenic bacteria were investigated. Results The pathogens of nosocomial infection were mainly isolated from sputum, urine, blood, accounted for 55.0%, 17.6%, and 10.6%, respectively. A total of 3 106 strains of pathogenic bacteria were isolated from 2013 to 2015, including Gram-negative bacteria(63.1%), Gram positive bacteria(21.2%), and fungi(15.7%). Gram negative bacteria were mainly Escherichia coli(18.1%), Acinetobacter baumanniis(14.0%), Klebsiella pneumoniae(13.2%), and Pseudomonas aeruginosa(9.7%). E. coli and K. pneumoniae were seriously resistant to ampicillin and piperacillin, and sensitive to amikacin, piperacillin/ tazobactam, meropenem, imipenem, and cefoperazone/sulbactam. A. baumanniis were seriously resistant to amoxicillin/ clavulanic acid, ampicillin, aztreonam and piperacillin, and sensitive to amikacin, cefoperazone / sulbactam. Gram positive bacteria were mainly Staphylococcus aureus(10.4%), which were seriously resistant to ampicillin, penicillin, erythromycin, clindamycin, and sensitive to quinupristin / dave leptin, teicoplanin, vancomycin, and linezolid. Conclusion The pathogenic bacteria in the First People’s Hospital of Xuzhou from 2013 to 2015 are mainly Gram negative bacteria, and the drug resistance is more common, so it is necessary to use the drug in accordance with the results of drug sensitivity test, and reduce hospital infection.
Pages: 2052-2056
Year: 2016 Issue: 12
Journal: World Phytomedicines
Keyword: pathogenic bacteria; drug resistance; hospital infection;
Abstract: Objective To investigate the distribution and drug resistance of pathogenic bacteria in the First People’s Hospital of Xuzhou from 2013 to 2015. Methods A retrospective analysis from January 2013 to December 2015 in the First People’s Hospital of Xuzhou were collected on the clinical data of patients with nosocomial infection, and the distribution and drug resistance of pathogenic bacteria were investigated. Results The pathogens of nosocomial infection were mainly isolated from sputum, urine, blood, accounted for 55.0%, 17.6%, and 10.6%, respectively. A total of 3 106 strains of pathogenic bacteria were isolated from 2013 to 2015, including Gram-negative bacteria(63.1%), Gram positive bacteria(21.2%), and fungi(15.7%). Gram negative bacteria were mainly Escherichia coli(18.1%), Acinetobacter baumanniis(14.0%), Klebsiella pneumoniae(13.2%), and Pseudomonas aeruginosa(9.7%). E. coli and K. pneumoniae were seriously resistant to ampicillin and piperacillin, and sensitive to amikacin, piperacillin/ tazobactam, meropenem, imipenem, and cefoperazone/sulbactam. A. baumanniis were seriously resistant to amoxicillin/ clavulanic acid, ampicillin, aztreonam and piperacillin, and sensitive to amikacin, cefoperazone / sulbactam. Gram positive bacteria were mainly Staphylococcus aureus(10.4%), which were seriously resistant to ampicillin, penicillin, erythromycin, clindamycin, and sensitive to quinupristin / dave leptin, teicoplanin, vancomycin, and linezolid. Conclusion The pathogenic bacteria in the First People’s Hospital of Xuzhou from 2013 to 2015 are mainly Gram negative bacteria, and the drug resistance is more common, so it is necessary to use the drug in accordance with the results of drug sensitivity test, and reduce hospital infection.
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