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The Diagnostic Significance of Red Blood Cell Volume Distribution Width in Non-ST-segment Elevation of Acute Coronary Syndrome
Author(s): 
Pages: 586-589,590
Year: Issue:  6
Journal: Journal of Clinical Transfusion and Laboratory Medicine

Keyword:  Red blood cell distribution widthNon- ST-segment elevation acute coronary syndromeCardiac troponin I;
Abstract: Objective To explore the predictive value of non-ST-segment elevation of acute coronary syndrome (NSTE-ACS)by detection of red blood cell volume distribution width(RDW)for determination of the cut off point.Methods From January2014 to June2015,146 NSTE-ACS cases were collected in observation group,and84 individuals were taken as control with non coronary heart disease confirmed by coronary angiography. The complete blood counting, cardiac troponin I(cTnI),and blood lipid wee tested.Results TC,LDL-C,cTnI,and RDW of NSTE-ACS group was higher than that of the control group,with a higher ratio of high blood pressure history or diabetes history(P<0.05). The RDW in those with the artery lesions of three branches was higher than with the single artery lesion and double branch lesions(P<0.05). RDW and cTnI were positively correlated(r=0.298,P<0.05). RDW receiver operating characteristic (ROC)curve analysis whowed thatthe best cut-off point of RDW for prediction of NSTE-ACS was11.93%,the area under the ROC curve was0.845(95% CI:0.792~0.898,P<0.05),specificity was82.90%,and sensitivity was72.62%. Patients with the RDW over11.93% presented a higher mortality or non-fatal myocardial infarction within30 days than those with the RDW below11.93%(P<0.05).Conclusion RDW is associated with the degree of lesion in NSTE-ACS, and may be used as auxiliary diagnosis and prognosis of NSTE-ACS.
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