Author(s): LI Li, SI Yu, Orthopedics Department No.3, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University
Pages: 1809-1811+1815
Year: 2016 Issue:  16
Journal: Journal of Hainan Medical College
Keyword:  Senile osteoporotic compression fractures; Qianggu Capsule; Salmon calcitonin injection; Bone metabolism;
Abstract: Objective: To analyze the effect of Qianggu Capsule combined with salmon calcitonin injection treatment on bone mineral density( BMD) and bone metabolism in patients with senile osteoporotic compression fractures. Methods: A total of 92 cases of patients with senile osteoporotic compression fractures were divided into observation group and control group( n = 46) according to random number table; control group received Qianggu Capsule treatment alone,observation group received Qianggu Capsule combined with salmon calcitonin injection treatment,and the differences in bone mineral density,bone metabolism indexes and CT-related parameters were compared between two groups. Results: BMD values of observation group after 3 courses and 6 courses of treatment were significantly higher than those of control group( P < 0. 05); serum bone gla protein( BGP) and parathyroid hormone( PTH) values of observation group after treatment were significantly higher than those of control group,CICP and CTX-Ⅰ values were significantly lower than those of control group,and urine D-Pyr value was significantly lower than that of control group( P < 0. 05); cancellous bone volume( CV) and CV / marrow cavity volume( MV) values of observation group after treatment were significantly higher than those of control group,and MV value was significantly lower than that of control group( P < 0. 05). Conclusions: Qianggu Capsule combined with salmon calcitonin injection can inhibit the disease progression in patients with senile osteoporotic compression fractures,optimize bone metabolism and promote osteogenesis,and it has positive clinical significance.