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eb bing du you dao xing gan rao su tong lu huo hua yu xi tong xing hong ban lang chuang de xiang guan xing
Author(s): 
Pages: 376-378
Year: Issue:  3
Journal: Acta Aacademiae Medical Qingdao Universitatis

Keyword:  红斑狼疮系统性疱疹病毒4型干扰素Ⅰ型综述;
Abstract: EB病毒感染在系统性红斑狼疮(SLE)发病中的作用以及机制一直是风湿病专家研究的热点之一。近年来研究显示,SLE病人血液中Ⅰ型干扰素水平升高,其下游基因过度活化。Ⅰ型干扰素通路活化是机体抗病毒感染重要的固有免疫机制,SLE病人是否存在EB病毒感染诱发的Ⅰ型干扰素通路活化、EB病毒是否通过该途径诱发SLE?本文就该方面的研究进展进行综述。
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