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Genotyping of Yersinia pestis by different regions and its epidemiological characteristics in Hebei province
Author(s): WANG Haifeng, LIU Hezhi, BAI Xuezuo, YANG Shunlin, ZHOU Song, HU Lele, LIU Yiyang, LI Yugui, SHI Xianming
Pages: 470-
473
Year: 2016
Issue:
5
Journal: Chinese Journal of Vector Biology and Control
Keyword: Yersinia pestis; Different segments; Genetic typing;
Abstract: 目的 研究河北省鼠疫疫源地鼠疫耶尔森菌(鼠疫菌)菌株的基因型别和遗传特征.方法 根据鼠疫基因组的22个差异区段和pMT1设计引物,对河北省鼠疫疫源地分离的116株菌株进行分析.结果 116株鼠疫菌株均缺乏DFR01、DFR06、DFR07、DFR13、DFR15~18片段,参考DFR基因分型系统,河北省鼠疫疫源地的菌株为基因17型,主要分布于内蒙古自治区化德县、白旗、太仆寺旗相邻的康保县北部.结论 河北省鼠疫菌菌株遗传稳定,仅有1个基因分型,疫情流行趋于平缓.
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