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Association of JWA gene polymorphism with susceptibility to digestive tract tumor
Author(s): DING Hou-you
Pages: 1096-
1097
Year: 2016
Issue:
10
Journal: Journal of Taishan Medical College
Keyword: HTF; gastrointestinal neoplasms; susceptibility; JWA gene; gene polymorphism;
Abstract: Objective:To analyze the relationship between JWA gene polymorphism and susceptibility of digestive tract tumors. Methods:From February 2011 to September 2013,181 patients with non-cancer patients were enrolled in the gen-eral disease group,170 patients with malignant tumors of the digestive tract,200 patients with malignant tumor and 200 normal controls as control group. JWA gene polymorphism Analysis,susceptibility analysis. Results:The-76G / C muta-tion had higher susceptibility,adjusted OR(95℅ CI) = 1. 99(1. 41 ~ 3. 47),and the risk was increased by about 2 times. Conclusion:JWA gene mutation and can increase the susceptibility of gastrointestinal cancer.
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