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Current status of treatment of refractory ascites in patients with liver cirrhosis
Author(s): Shao Jing, Zhang Lei, Han Guohong, Fan Daiming
Pages: 721-
723
Year: 2016
Issue:
10
Journal: Chinese Journal of Hepatology
Keyword: Liver cirrhosis; Ascites; Therapy;
Abstract: Ascites is a common clinical manifestation of cirrhotic portal hypertension,and about 60%-80% of cirrhotic patients develop the symptom of ascites within 10 years.Once ascites occurs,the 5-year survival rate is reduced from 80% to 50%.With the progression of liver diseases,approximately 5%-10% of patients with ascites develop refractory ascites,and the median survival time is only 6-12 months.This article reviews the definition and diagnosis of refractory ascites,evaluation of prognostic factors,and treatment regimens,including large-volume paracentesis combined with protein supplementation,transjugular intrahepatic portosystemic shunt,and liver transplantation.
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