Author(s): Lu Xianghong, Department of Anesthesiology, the Affiliated Hospital of Yuncheng City Medical School
Pages: 53+55
Year: 2016 Issue:  20
Journal: Chinese Community Doctors
Keyword:  Breast cancer radical operation; Kappa receptors; Dynorphin; Intravenous anesthesia;
Abstract: Objective:To observe the effect of intravenous anesthesia on the skin dynorphin and kappa receptors expression of the patients with breast cancer radical operation.Methods:60 patients with breast cancer radical operation were selected.They were randomly divided into A group and B group. A group was given fentanyl and propofol intravenous injection.B group was given ketamine and propofol intravenous injection.The skin dynorphin and kappa receptors expression were determined before and after operation.Results:The skin dynorphin and kappa receptors expression after operation in two groups were significantly higher than those before operation(P<0.05).Conclusion:Skin dynorphin and kappa receptors expression increase is connected with surgical stimulation,and the effect of intravenous anesthesia on dynorphin and kappa receptors expression increase is not obvious.