Clinical value of serum calcitonin in the guidance of anti infection treatment of severe patients in ICU of department of internal medicine
Author(s): Dong Junlin, Department of Internal Medicine, the People’s Hospital of Wusu City Xinjiang
Pages: 134+136
Year: 2016 Issue: 21
Journal: Chinese Community Doctors
Keyword: Serum calcitonin; Department of internal medicine; Severe infection;
Abstract: Objective:To explore the clinical value of serum procalcitonin(PCT) in the guidance of anti infection treatment of severe patients in ICU of department of internal medicine.Methods:110 patients with severe infection were selected.They were randomly divided into the control group and the observation group.The control group was given routine antibiotic therapy.In the observation group,the patients with serum PCT less than 0.25 μg/L were given non antibiotic treatment,and the patients with serum PCT more than 0.25 μg/L were given antibiotic treatment.We compared the treatment effects of two groups.Results:In the observation group,the mortality rate of 5.45% was significantly lower than 12.73% of the control group,and the use time of antibiotics and hospitalization time were significantly shorter than the control group(P<0.05).After treatment,the CRP and WBC count of the two groups were significantly reduced(P<0.05),but there was no significant difference between the groups(P>0.05).In the observation group,the level of PCT after treatment was significantly lower than that before treatment(P<0.05).Conclusion:PCT was an important evaluation index for infection situation of severe patients in ICU,and it had important guiding significance for the use of antibiotics.
Pages: 134+136
Year: 2016 Issue: 21
Journal: Chinese Community Doctors
Keyword: Serum calcitonin; Department of internal medicine; Severe infection;
Abstract: Objective:To explore the clinical value of serum procalcitonin(PCT) in the guidance of anti infection treatment of severe patients in ICU of department of internal medicine.Methods:110 patients with severe infection were selected.They were randomly divided into the control group and the observation group.The control group was given routine antibiotic therapy.In the observation group,the patients with serum PCT less than 0.25 μg/L were given non antibiotic treatment,and the patients with serum PCT more than 0.25 μg/L were given antibiotic treatment.We compared the treatment effects of two groups.Results:In the observation group,the mortality rate of 5.45% was significantly lower than 12.73% of the control group,and the use time of antibiotics and hospitalization time were significantly shorter than the control group(P<0.05).After treatment,the CRP and WBC count of the two groups were significantly reduced(P<0.05),but there was no significant difference between the groups(P>0.05).In the observation group,the level of PCT after treatment was significantly lower than that before treatment(P<0.05).Conclusion:PCT was an important evaluation index for infection situation of severe patients in ICU,and it had important guiding significance for the use of antibiotics.
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