Effect of Huaiqihuang granules in preventing and treating bronchial asthma and influence on immunological function in children
Author(s): Huang Han, Zhang Xiangfeng, Lu Hongxia
Pages: 1367-1371
Year: 2016 Issue: 9
Journal: China Medicine
Keyword: Huaiqihuang granules; Bronchial asthma; children; Immunological function;
Abstract: Objective To investigate the effect of Huaiqihuang granules in preventing and treating bronchial asthma and its influence on immunological function in children.Methods Totally 64 cases with bronchial asthma from January 2013 to January 2015 were randomly divided into control group (n =32) given conventional drug aminophylline (1-＜ 3 years old,0.1 g/time,2 times/d;＞ 3 years old,0.2 g/time,2 times/d)and observation group (n =32) given Huaiqihuang granules (1-＜ 3 years old,0.5 package/time,2 times/d;＞3 years old,1 package/time,2 times/d).The treatment lasted for 2 months.The clinical efficacy and control degree of asthma were compared between groups;the immunological indexes were measured before and after treatment in observation group.Results The effective rate in observation group was significantly higher than that in control group [96.9％ (31/32) vs 78.1％ (25/32)] (P ＜0.05).The symptom degree of asthma in daytime in observation group was significantly lower than that in control group [(0.46 ±0.13) scores vs (0.98 ±0.20) scores](P ＜ 0.05).In observation group,the levels of IgA and IgM were significantly reduced,the level of IgG was significantly increased after treatment compared with those before treatment [(1.15 ± 0.14) mg/L vs (1.23 ±0.12) mg/L,(1.28 ±0.20) mg/L vs (1.32 ±0.42) mg/L,(9.24 ±0.16) mg/L vs (7.04 ± 1.14) mg/L](P ＜ 0.05),the levels of total T cells,suppressor T cells,helper T cells,nature killer cells were significantly increased,the level of total B cells was significantly reduced after treatment compared with those before treatment [(68.6±2.3)％ vs (61.2 ±5.3)％,(25.8 ±0.4)％ vs (20.0 ±5.6)％,(35.4 ±2.5)％ vs (31.6±3.3)％,(15.3 ± 1.7)％ vs (10.2±4.1)％,(13.6 ± 1.4)％ vs (16.9 ±3.6)％] (P ＜0.05).Conclusion Huaiqihuang granules can effectively prevent and treat bronchial asthma,and improve the immunological function in children.
Pages: 1367-1371
Year: 2016 Issue: 9
Journal: China Medicine
Keyword: Huaiqihuang granules; Bronchial asthma; children; Immunological function;
Abstract: Objective To investigate the effect of Huaiqihuang granules in preventing and treating bronchial asthma and its influence on immunological function in children.Methods Totally 64 cases with bronchial asthma from January 2013 to January 2015 were randomly divided into control group (n =32) given conventional drug aminophylline (1-＜ 3 years old,0.1 g/time,2 times/d;＞ 3 years old,0.2 g/time,2 times/d)and observation group (n =32) given Huaiqihuang granules (1-＜ 3 years old,0.5 package/time,2 times/d;＞3 years old,1 package/time,2 times/d).The treatment lasted for 2 months.The clinical efficacy and control degree of asthma were compared between groups;the immunological indexes were measured before and after treatment in observation group.Results The effective rate in observation group was significantly higher than that in control group [96.9％ (31/32) vs 78.1％ (25/32)] (P ＜0.05).The symptom degree of asthma in daytime in observation group was significantly lower than that in control group [(0.46 ±0.13) scores vs (0.98 ±0.20) scores](P ＜ 0.05).In observation group,the levels of IgA and IgM were significantly reduced,the level of IgG was significantly increased after treatment compared with those before treatment [(1.15 ± 0.14) mg/L vs (1.23 ±0.12) mg/L,(1.28 ±0.20) mg/L vs (1.32 ±0.42) mg/L,(9.24 ±0.16) mg/L vs (7.04 ± 1.14) mg/L](P ＜ 0.05),the levels of total T cells,suppressor T cells,helper T cells,nature killer cells were significantly increased,the level of total B cells was significantly reduced after treatment compared with those before treatment [(68.6±2.3)％ vs (61.2 ±5.3)％,(25.8 ±0.4)％ vs (20.0 ±5.6)％,(35.4 ±2.5)％ vs (31.6±3.3)％,(15.3 ± 1.7)％ vs (10.2±4.1)％,(13.6 ± 1.4)％ vs (16.9 ±3.6)％] (P ＜0.05).Conclusion Huaiqihuang granules can effectively prevent and treat bronchial asthma,and improve the immunological function in children.
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