To Investigate the Small Dose of Olanzapine Combined with Pa Rossi Dean on the Clinical Effect of Treatment of Senile Depression
Author(s): MENG Fan-j ie
Pages: 103-105
Year: 2016 Issue: 25
Journal: China Foreign Medical Treatment
Keyword: Senile depression; Pa Rossi Dean; Olanzapine;
Abstract: Objective To observe the clinical effect of small dose of olanzapine combined with Pa Rossi Dean on the treat-ment of senile depression. Methods From January 2012 to January 2016 in our hospital for senile depression 102 cases were divided into two groups and studied, divided into control group and treatment group according to the computer digital method, each among 51 patients and control group separately using paroxetine treatment, the treatment group with small dose of olanzapine combined with paroxetine in the treatment by HAMD and Tess, evaluates and compares the two groups curative effect and adverse reaction. Results Convenient selection after treatment for 2 weeks HAMD score was (21.39 ± 2.47) points, for 4 weeks HAMD score was (16.29 ± 3.28) points, for 8 weeks HAMD score was (9.52 ± 2.40) points; the control group were (17.28 ± 2.38) points, (11.29 ± 3.18) points, (7.93 ± 2.00) points, by comparison, the control group 2 weeks, 4 weeks HAMD score is still higher than the treatment group (P<0.05), but the two groups 8 weeks after HAMD score, the difference was not statistically significant (P>0.05); the treatment group, the total efficiency of 94.1% was signifi-cantly higher than 72.5%, a significant difference between the groups was statistically significant (P<0.05) [see given the study of specific data, and to make consequential amendments] in the English summary. Conclusion Senile depression in patients with small dose olanzapine combined with paroxetine in the treatment scheme can effectively ameliorate clinical symptoms in a short period of time, in order to improve the therapeutic effect. It is safe and effective, and worthy of clinical application and promotion.
Pages: 103-105
Year: 2016 Issue: 25
Journal: China Foreign Medical Treatment
Keyword: Senile depression; Pa Rossi Dean; Olanzapine;
Abstract: Objective To observe the clinical effect of small dose of olanzapine combined with Pa Rossi Dean on the treat-ment of senile depression. Methods From January 2012 to January 2016 in our hospital for senile depression 102 cases were divided into two groups and studied, divided into control group and treatment group according to the computer digital method, each among 51 patients and control group separately using paroxetine treatment, the treatment group with small dose of olanzapine combined with paroxetine in the treatment by HAMD and Tess, evaluates and compares the two groups curative effect and adverse reaction. Results Convenient selection after treatment for 2 weeks HAMD score was (21.39 ± 2.47) points, for 4 weeks HAMD score was (16.29 ± 3.28) points, for 8 weeks HAMD score was (9.52 ± 2.40) points; the control group were (17.28 ± 2.38) points, (11.29 ± 3.18) points, (7.93 ± 2.00) points, by comparison, the control group 2 weeks, 4 weeks HAMD score is still higher than the treatment group (P<0.05), but the two groups 8 weeks after HAMD score, the difference was not statistically significant (P>0.05); the treatment group, the total efficiency of 94.1% was signifi-cantly higher than 72.5%, a significant difference between the groups was statistically significant (P<0.05) [see given the study of specific data, and to make consequential amendments] in the English summary. Conclusion Senile depression in patients with small dose olanzapine combined with paroxetine in the treatment scheme can effectively ameliorate clinical symptoms in a short period of time, in order to improve the therapeutic effect. It is safe and effective, and worthy of clinical application and promotion.
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