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lao nian ji xing que xue xing nao zu zhong bing ren xin zuo zhi shu yu xue guan nei pi sheng chang yin zi d- er ju ti shui ping de xiang guan xing yan jiu
Author(s): 
Pages: 1805-1806+1810
Year: Issue:  15
Journal: Research of Traditional Chinese Medicine

Keyword:  老年缺血性脑卒中心踝血管指数血管内皮生长因子D-二聚体;
Abstract: 目的探讨60岁以上老年人急性缺血性脑卒中病人心踝血管指数(CAVI)与血清血管内皮生长因子(VEGF)、D-二聚体的相关性。方法选取老年急性脑卒中病人62例为脑卒中组,同期60名老年健康体检者为对照组。采用动脉硬化检测仪(福田VS1000)检测CAVI,用双抗体夹心ELISA法分别检测两组病人血清中VEGF和D-二聚体的含量。结果心踝血管指数脑卒中组与对照组比较,差异有统计学意义(P<0.05);脑卒中组血清VEGF和D-二聚体水平与对照组比较,差异有统计学意义(P<0.05);相关因素分析脑卒中组病人CAVI与VEGF、D-二聚体呈显著正相关(分别为r=0.539,P<0.01;r=0.562,P<0.01)。结论老年急性脑卒中病人CAVI与VEGF、D-二聚体水平明显增高,呈显著正相关性,CAVI测量对判断老年急性缺血性脑卒中病人动脉硬化程度及预后有一定的临床指导意义。
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