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Effects of Xylene, Anthracene, and Benzo [α]pyrene on Enzymatic Activities of SOD and CAT in the Japanese Scallop (Mizuhopecten yessoensis) Serums
Author(s): 
Pages: 289-294
Year: Issue:  1
Journal: Asian Journal of Ecotoxicolog

Keyword:  xyleneanthracenebenzo[α]pyreneJapanese scallop (Mizuhopecten yessoensis)oxidative stressSODCAT;
Abstract: 以虾夷扇贝(Mizuhopecten yessoensis)为受试生物,设置3种不同浓度的二甲苯、蒽、苯并[α]芘处理健康的虾夷扇贝,检测血清中超氧化物歧化酶(SOD)、过氧化氢酶(CAT)活性变化情况,结果发现:0.01~1.0 mg·L-1的二甲苯、0.002~0.2 mg·L-1的蒽、0.001~ 0.1 mg·L-1的苯并[α]芘处理6、12 h后,虾夷扇贝血清SOD活性升高,处理12 h后对血清SOD活性诱导率均高于处理6h的;处理6h后,血清CAT活性降低,而处理12 h后,血清CAT活性升高;具有显著的剂量-效应关系和时效关系,表明二甲苯、蒽、苯并[α]芘对虾夷扇贝具有氧化胁迫作用,可能导致其氧化损伤.相关性分析发现,3种污染物处理6h后,血清SOD活性与CAT活性变化呈显著负相关;而处理12h后,血清SOD活性与CAT活性变化呈显著正相关.上述结果为开展二甲苯、蒽、苯并[α]芘对海洋贝类毒性评价提供基础数据.
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