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Tiaojing decoction in treatment of polycystic ovary syndrome
Author(s): 
Pages: 695-699
Year: Issue:  7
Journal: Jilin Journal of Traditional Chinese Medicine

Keyword:  Tiaojing decoctionPCOSpregnancy ratemenstrual recovery ratefollicle quality;
Abstract: Objective To observe the traditional Chinese medicine Tiaojing decoction on polycystic ovary syndrome (PCOS)in the treatment of infertility,and to explore its mechanism. Methods Selected 86 cases patients with PCOS were randomly divided them into observation group and control group with 43 cases in each group. The control group was treated with basic treatment method:let the patients taking ethinylestradiol and cyproterone acetate tablets and clomi-phene citrate,and injected menotropins injection(the period of treatment was 3 menstrual cycle). On the basis of the basic treatment,the observation group used Tiaojing decoction(the period of treatment was 3 menstrual cycle). Moni-tored the development of follicle by B ultrasound,made a determination of dominant follicular membrane blood flow,and recorded the pulsatile index(PI)and resistance index(RI);the levels of fasting blood glucose(FBG),pulsatility index (PI)and fasting insulin(FINS)were monitored and compared with the patients before and after treatment,and calcu-late insulin resistance index(HOMA - IR);monitored and recorded the level of human chorionic gonadotropin(HCG) (injection day),corpus(LH),estradiol(E2 ),serum testosterone(T)and follicle stimulating hormone(FSH);After treatment,the patients with menstrual recovery rate,ovulation rate and pregnancy rate were recorded. Results After made a treatment to the two groups of patients,the rate of menstruation recovery(93. 02% ),ovulation(86. 04% )and pregnancy(72. 09% )were higher than those of the control group(69. 77% ),the difference was statistically significant (P <0. 01);PI was significantly higher than before treatment,and the observation group was higher than the control group,the difference was statistically significant;RI was significantly lower than before treatment,and the observation group was lower than the control group,the difference was statistically significant(P < 0. 001);the levels of FSH,LH and E2 of the observation group were significantly higher than those in the control group,and the levels of T was signifi-cantly lower than those in the control group,all the differences were statistically significant(P < 0. 001);the levels of FINS,IR and LP in the two groups were significantly lower than those in the control group,and the observation group was lower than that of the control group(P <0. 001). Conclusion Basic treatment plus up to the treatment of decoction, can improve the ovarian blood flow,Kaohsiung hormone syndrome,insulin resistance quality of the patients,improve the quality of ovarian follicles and it plays a significant role in ovulation rate and pregnancy rate.
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