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Genetic studies of 15 loci in southern China Han population and Li population
Author(s): 
Pages: 207-209,212
Year: Issue:  4
Journal: JOURNAL OF FORENSIC MEDICINE

Keyword:  IdentifilerTM复合扩增荧光标记STR基因座遗传多态性法医学应用;
Abstract: 目的调查南方汉族、黎族人群无关个体的15个STR基因座(D8S1179、D21S11、D7S820、CSF1PO、D3S1358、TH01、D13S317、D16S539、D2S1338、D19S433、vWA、TPOX、D18S51、D5S818、FGA)多态性,研究其在法医学检验中的应用价值.方法应用AmpFlSTR IdentifilerTM荧光标记复合扩增系统对南方332例汉族、334例黎族无关个体血样DNA进行15个STR基因座的复合扩增,用ABI 3100遗传分析仪对扩增产物进行检测,用GeneScan、GenoTyper软件进行基因分型,统计计算15个STR基因座的群体遗传学参数.结果IdentifilerTM荧光标记系统的15个STR基因座在南方汉族、黎族人群的累积偶合率分别为4.94×10-17、2.50×10-17,累积非父排除率分别为0.9999989、0.999998 8.结论该15个STR基因座足可满足南方汉族、黎族法医学的个体识别及亲权鉴定的需要.
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