Clinical study on Tanreqing Injection combined with moxifloxacin in treatment of senile community acquired pneumonia
Author(s): JING Jun-hu, LI Li-yu
Pages: 788-791
Year: 2016 Issue: 6
Journal: World Phytomedicines
Keyword: Tanreqing Injection; Moxifloxacin Hydrochloride and Sodium Chloride Injection; Moxifloxacin Hydrochloride Tablets; senile community acquired pneumonia; clinical efficacy; relief of signs; laboratory examination indexes;
Abstract: Objective To explore the clinical efficacy and safety of Tanreqing Injection combined with moxifloxacin in treatment of senile community acquired pneumonia. Methods Patients (86 cases) with senile community acquired pneumonia in Tianjin Fourth Center Hospital from June 2014 to October 2015 were randomly divided into control and treatment groups, and each group had 43 cases. The patients in the control group were iv administered with Moxifloxacin Hydrochloride and Sodium Chloride Injection 0.4 g/time, once daily. If the patients got better during the treatment, antibiotics could be changed to Moxifloxacin Hydrochloride Tablets 0.4 g/time, once daily. The patients in the treatment group were iv administered with Tanreqing Injection on the basis of the control group, 20 mL/time adding into 250 mL physiological saline, once daily. Two groups were treated for 10 d. After treatment, the clinical efficacies were evaluated, and the changes of clinical symptoms, relief of signs, and laboratory examination indexes were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 88.37%and 97.67%, respectively, and there were differences between two groups (P<0.05). Antipyretic action, ease of cough, and pulmonary rales disappeared time in treatment group were better than those in the control group, with the significant difference between two groups (P<0.05). After treatment for 3 and 10 d, the count of white blood cells, neutrophils ratio, and CRP levels in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Tanreqing Injection combined moxifloxacin has good clinical effect in treatment of senile community acquired pneumonia , and can improve symptoms and laboratory examination indexes with less adverse reactions, which has a certain clinical application value.
Pages: 788-791
Year: 2016 Issue: 6
Journal: World Phytomedicines
Keyword: Tanreqing Injection; Moxifloxacin Hydrochloride and Sodium Chloride Injection; Moxifloxacin Hydrochloride Tablets; senile community acquired pneumonia; clinical efficacy; relief of signs; laboratory examination indexes;
Abstract: Objective To explore the clinical efficacy and safety of Tanreqing Injection combined with moxifloxacin in treatment of senile community acquired pneumonia. Methods Patients (86 cases) with senile community acquired pneumonia in Tianjin Fourth Center Hospital from June 2014 to October 2015 were randomly divided into control and treatment groups, and each group had 43 cases. The patients in the control group were iv administered with Moxifloxacin Hydrochloride and Sodium Chloride Injection 0.4 g/time, once daily. If the patients got better during the treatment, antibiotics could be changed to Moxifloxacin Hydrochloride Tablets 0.4 g/time, once daily. The patients in the treatment group were iv administered with Tanreqing Injection on the basis of the control group, 20 mL/time adding into 250 mL physiological saline, once daily. Two groups were treated for 10 d. After treatment, the clinical efficacies were evaluated, and the changes of clinical symptoms, relief of signs, and laboratory examination indexes were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 88.37%and 97.67%, respectively, and there were differences between two groups (P<0.05). Antipyretic action, ease of cough, and pulmonary rales disappeared time in treatment group were better than those in the control group, with the significant difference between two groups (P<0.05). After treatment for 3 and 10 d, the count of white blood cells, neutrophils ratio, and CRP levels in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Tanreqing Injection combined moxifloxacin has good clinical effect in treatment of senile community acquired pneumonia , and can improve symptoms and laboratory examination indexes with less adverse reactions, which has a certain clinical application value.
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