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BMP-6 Expression in Breast Cancers and Cancer-Adjacent Tissues by Immunohistochemical Staining
Author(s): 
Pages: 55-57
Year: Issue:  2
Journal: Journal of Tangshan Teachers College

Keyword:  BMP-6免疫组化染色乳腺癌;
Abstract: 通过免疫组化染色方法检测了BMP-6在乳腺癌,癌旁乳腺组织和正常淋巴结组织的表达.免疫组化结果显示,BMP-6在13例癌旁乳腺组织(纤维脂肪组织)中表达均呈现阴性;在9例正常淋巴结组织中表达均呈现阳性;但在34例乳腺癌(非特殊性浸润性导管癌)中的阴性表达率26.5%;在9例乳腺癌(淋巴结转移性非特殊性浸润性导管癌)阴性表达率33.3%;在35例癌旁乳腺组织(上皮细胞)中阴性表达率14.3%.结果表明BMP-6在乳腺癌、癌旁乳腺组织和正常淋巴结组织的表达存在明显差异,BMP-6在乳腺癌中表达的缺失是诱发乳腺癌发生重要原因.
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