Mechanism of curcumin resisting esophageal cancer
Author(s): Tian Ruonan, Sun Jianjing, Zhang Linxi
Pages: 379-381
Year: 2016 Issue: 5
Journal: Journal of International Oncology
Keyword: Curcumin; Esophageal neoplasms;
Abstract: Curcumin can suppress the proliferation of esophageal cancer cells by inducing cell cycle arrest and blocking Notch signaling pathway,and can inhibit the invasiveness of esophageal cancer cells by inhibiting the nuclear factor-κB (NF-κB) signaling pathway and suppressing the formation of tumor blood vessels and inhibiting matrix metalloproteinase (MMP).Curcumin can also regulate apoptosis of esophageal cancer cells by changing the expression and localization of nucleophosmin.
Pages: 379-381
Year: 2016 Issue: 5
Journal: Journal of International Oncology
Keyword: Curcumin; Esophageal neoplasms;
Abstract: Curcumin can suppress the proliferation of esophageal cancer cells by inducing cell cycle arrest and blocking Notch signaling pathway,and can inhibit the invasiveness of esophageal cancer cells by inhibiting the nuclear factor-κB (NF-κB) signaling pathway and suppressing the formation of tumor blood vessels and inhibiting matrix metalloproteinase (MMP).Curcumin can also regulate apoptosis of esophageal cancer cells by changing the expression and localization of nucleophosmin.
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