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mtor xin hao tong lu yu yi xian ai yan jiu jin zhan
Author(s): 
Pages: 92-95
Year: Issue:  2
Journal: Acta Academiae Medicinae Jiangxi

Keyword:  胰腺癌mTOR 信号通路mTOR 抑制剂;
Abstract: 雷帕霉素靶蛋白(mammalian target of rapamycin,mTOR)信号通路在胰腺癌中过度激活,可作为胰腺癌的靶向治疗的靶点。近年来研究显示,雷帕霉素及衍生物无论是单药使用还是和其他细胞毒性药物联合使用,都能明显抑制胰腺癌生长,mTOR 抑制剂在胰腺癌的治疗中显示出良好的应用前景。本文就 mTOR 信号转导通路及mTOR 抑制剂在胰腺癌治疗中的临床应用前景进行综述。
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