The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
caco-2 xi bao mo xing zai zhong yao zhuan yun ji zhi ji xiang hu zuo yong ji zhi zhong de yan jiu jin zhan
Author(s): 
Pages: 96-98
Year: Issue:  2
Journal: Acta Academiae Medicinae Jiangxi

Keyword:  Caco-2 细胞模型中药转运机制中药药物相互作用中药药物外排机制;
Abstract:  Caco-2细胞是通过克隆人类的结肠癌细胞而来。Caco-2细胞不仅在显微镜下形态、极性及胞饮功能与小肠上皮细胞相似,而且其含有的转运系统和代谢酶也与小肠刷状缘上皮相似[1]。药物在透过Caco-2细胞模型的体外过程与药物口服后,在小肠内的吸收和代谢有良好的相关性[2]。因此,Caco-2细胞模型常用于药物的跨膜转运实验,从而可进一步预测药物在人小肠中吸收情况。
Related Articles
No related articles found