Study Advances on Cucurbitadienol and its Biosynthesis
Author(s): LUO Zu-liang, ZHANG Kai-lun, MA Xiao-jun, GUO Yu-hua, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Yunnan Branch Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences
Pages: 179-182
Year: 2016 Issue: 2
Journal: Pharmaceutical Biotechnology
Keyword: Cucurbitadienol; Pharmacological activity; Biosynthetic pathway; Gene; Biosynthesis; Reviews;
Abstract: Cucurbitadienol a cucurbitane-type tetracyclic triterpenoid,has been isolated from a variety of cucurbitaceae plants. The research of pharmacological activity showed that cucurbitadienol has significant anti-inflammatory and anti-tumor effects. Furthermore,cucurbitadienol is a key intermediate for the biosynthesis of cucurbitacins. This paper reviews the distribution of cucurbitadienol in plants and its pharmacological activities,biosynthetic pathway,gene clone and expression,analysis methods,synthesis methods,etc. Summarizing the current research status and making a prospect in development and utilization of cucurbitadienol.
Pages: 179-182
Year: 2016 Issue: 2
Journal: Pharmaceutical Biotechnology
Keyword: Cucurbitadienol; Pharmacological activity; Biosynthetic pathway; Gene; Biosynthesis; Reviews;
Abstract: Cucurbitadienol a cucurbitane-type tetracyclic triterpenoid,has been isolated from a variety of cucurbitaceae plants. The research of pharmacological activity showed that cucurbitadienol has significant anti-inflammatory and anti-tumor effects. Furthermore,cucurbitadienol is a key intermediate for the biosynthesis of cucurbitacins. This paper reviews the distribution of cucurbitadienol in plants and its pharmacological activities,biosynthetic pathway,gene clone and expression,analysis methods,synthesis methods,etc. Summarizing the current research status and making a prospect in development and utilization of cucurbitadienol.
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