Logistic regression analysis of risk factors of recurrence of choledocholithiasis after choledocholithotomy
Author(s): Zhen-yi Li, Li Tao, Department of General Surgery, the First People’s Hospital of Shizuishan Affiliated to Ningxia Medical University
Pages: 122-126
Year: 2016 Issue: 11
Journal: China Journal of Modern Medicine
Keyword: choledocholithiasis; choledocholithotomy; recurrence; risk factor;
Abstract: Objective To explore the risk factors of recurrence of choledocholithiasis after choledocholithotomy. Methods The clinical data of 214 patients with common bile duct calculi who received choledocholithotomy from September 2004 to September 2014 were retrospectively analyzed. The 80 cases with choledocholithiasis recurrence were taken as observation group, the 134 cases without recurrence as control group.The clinical data of the two groups were compared. For single-factor analysis t and χ~2 tests were adopted,while logistic regression analysis was used for multiple-factor analysis. Results The results of single-factor analysis showed that the two groups had statistically significant differences in age, HBV infection, periampullary diverticula, infection of biliary tract, biliary surgery history, gallstones, gallbladder excision, diameter of common bile duct ≥1.5 cm, bile duct angle ≤120°, biliary stricture, papillary stenosis, Oddis sphincter dysfunction, stone with diameter ≥1 cm, number of stone ≥2(P < 0.05). Logistic regression analysis showed that biliary surgery history [OR= 2.692(95% CI: 1.906, 6.884), P = 0.024], periampullary diverticula [OR=3.201(95% CI: 1.993, 6.756), P = 0.032], diameter of common bile duct ≥1.5 cm [ OR= 3.234(95% CI:1.742, 6.875), P = 0.024] and bile duct angle ≤120° [OR= 2.305(95% CI: 1.822, 6.901), P = 0.021] were the independent risk factors of the recurrence of choledocholithiasis after choledocholithotomy. Conclusions There are many influence factors of recurrence of common bile duct calculi after choledocholithotomy. The preventive measures should be strengthened, such as controlling biliary infection, relieving biliary obstruction and improving biliary dynamics to solve the recurrence problems after choledocholithotomy.
Pages: 122-126
Year: 2016 Issue: 11
Journal: China Journal of Modern Medicine
Keyword: choledocholithiasis; choledocholithotomy; recurrence; risk factor;
Abstract: Objective To explore the risk factors of recurrence of choledocholithiasis after choledocholithotomy. Methods The clinical data of 214 patients with common bile duct calculi who received choledocholithotomy from September 2004 to September 2014 were retrospectively analyzed. The 80 cases with choledocholithiasis recurrence were taken as observation group, the 134 cases without recurrence as control group.The clinical data of the two groups were compared. For single-factor analysis t and χ~2 tests were adopted,while logistic regression analysis was used for multiple-factor analysis. Results The results of single-factor analysis showed that the two groups had statistically significant differences in age, HBV infection, periampullary diverticula, infection of biliary tract, biliary surgery history, gallstones, gallbladder excision, diameter of common bile duct ≥1.5 cm, bile duct angle ≤120°, biliary stricture, papillary stenosis, Oddis sphincter dysfunction, stone with diameter ≥1 cm, number of stone ≥2(P < 0.05). Logistic regression analysis showed that biliary surgery history [OR= 2.692(95% CI: 1.906, 6.884), P = 0.024], periampullary diverticula [OR=3.201(95% CI: 1.993, 6.756), P = 0.032], diameter of common bile duct ≥1.5 cm [ OR= 3.234(95% CI:1.742, 6.875), P = 0.024] and bile duct angle ≤120° [OR= 2.305(95% CI: 1.822, 6.901), P = 0.021] were the independent risk factors of the recurrence of choledocholithiasis after choledocholithotomy. Conclusions There are many influence factors of recurrence of common bile duct calculi after choledocholithotomy. The preventive measures should be strengthened, such as controlling biliary infection, relieving biliary obstruction and improving biliary dynamics to solve the recurrence problems after choledocholithotomy.
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